Moringa An Anti-Cancer Agent Against Breast And Prostate Cancers – A New Superfood

In this evidence based article regarding functional foods (superfoods) effects on our body systems, I will briefly discuss some therapeutic use of Moringa.

After reading this article, you will become more confident to add Moringa in your daily diet.

Here are several convincing research evidence that supports these incredible benefits of moringa.

Moringa might prevent some types of cancer cell growth

As I said, there are many research studies conducted on human cancer cell lines, including:

• Hepatocarcinoma,
• Colorectal carcinoma,
• Breast carcinoma,
• Ovarian,
• Prostate and
• Lung cancer cell line [30, 31].

Every studies results demonstrated that to some extent Moringa might be able to prevent at least some cancer cell growth.

The moringa leaf extract might be effective against leukemia (up to a point) due to its potent cytotoxic effects on cancer cell growth [30].

Since all standard cancer medications have some side effects see if your medical doctor approves it, you can add it as a chemo preventive agent.

I personally prefer moringa because it is relatively safe for human use and it does not cause any long term adverse or side effects [26].

Of course in the case of cancer, is not just nutrition which can help – cancer is a multi-factorial disease.

But, to some extent moringa can improve some of these factors by inducing:

• Apoptosis,
• Carcinogen detoxification,
• Anti-tumour cell proliferation, and
• Anti-inflammatory activities.

A gift of Moringa leaf supplement can act as a kiss of the good life to any of your close relatives, family members and friends.

This simple gift can actually help them to activate their body system against carcinogenesis by inhibiting:

• tumour angiogenesis and
• carcinogen activation [32].

Cell protection from free-radical damage

All health-conscious people know about ‘antioxidant’, which has a high potential to provide cell protection by preventing free radical damage.

To boost your knowledge, I will briefly explain to you why these free radicals are harmful to our body.

In brief the free radical formation is a continuous cellular consequence that occurs due to:

  • normal essential metabolic processes or
  • exposure to harmful rays, or due to
  • chemicals,
  • pollutants,
  • cigarette smoking and even
  • alcohol consumption
  • etc.

Free radicals are unstable and highly reactive, and usually damage our body’s DNA, lipids [fats], proteins, and carbohydrate structures [sugar].

To some extent this burden of excess free radicals are responsible for increasing the risk of cancer and atherosclerosis by inducing:

• Chromosomal defects,
• Oncogene activation of genes which could potentially cause cancer and,
• Modulate arterial walls to impart endothelial cell injury respectively [33].

Moringa has potent antioxidant properties and it is effective to prevent free radical-induced DNA damage by decreasing free radical levels [30].

But, also lowers, controls and eliminates some of the inflammation.

We mostly believe that infection always brings inflammation.

But,

Did you know that many non-infectious diseases like arthritis, edema, tumour, cancer, autoimmune diseases also have an inflammatory association [34]?

The inflammation is just one of the underlying causes for a wide range of diseases including:

• Arthritis,
• Asthma,
• Edema and
• Autoimmune conditions like Rheumatoid arthritis, Type 1 diabetes, Hashimoto’s thyroiditis, Celiac disease, Psoriasis [35].

It has been proven that Moringa has the ability to inhibit some inflammatory mediators such as cytokine production in the human body.

Quercetin, the phytochemical present in Moringa leaf extract can reduce the inflammatory process by inhibiting the action of neutral factor kappa-beta (NF-κB).

NF-κB is a pro-inflammatory mediator and activation of NF-κB leads to inflammation and also increase free radicals levels [36, 37].

Moringa leaves also improve white blood cell count and activate the immune response [38].

Altogether, moringa lowers, controls and eliminates at least some inflammation.

Improve brain function – and how it increases one’s brain performance at work

Ageing is one of the common causes of the neurodegenerative condition.

Moringa acts as a neuroprotector and improves cognitive activity.

Moringa exerts its therapeutic effects on hippocampal neurons, which are present in our hippocampus, the important structure of the brain and plays a critical role in the formation of new memories [39].

It significantly enhances neuronal structural growth.

The antioxidant property of Moringa reduces oxidative stress in the brain.
Moringa Surgery

These positive neurological benefits improve brain functioning [40].

Working memory is always necessary for learning and achieves success at work.

Research evidence showed the antioxidant and nootropic (brain booster) activities of Moringa enhances memory [41].

Therefore,

Moringa may be an unusual solution to unfold the technical hitch at your workplace, by boosting your learning ability.

Cardiovascular disease

Chronic dyslipidemia increases the risk of cardiovascular disease.

Dyslipidemia is characterised by an increased level of triglycerides, phospholipids, and cholesterol in the blood.

It has been found that the plasma level of low-density lipoprotein-cholesterol [LDL – poor cholesterol] is higher in people in the UK [42].

Moringa leaves have a potential role to modulate the reverse cholesterol transport [43].

Reverse cholesterol transport is a physiological mechanism through which our body can remove some excess cholesterol including triglycerides and low-density lipo-proteins from different tissues.

It also transports them to liver for removal through the gall bladder, whereas high-density lipoprotein restores into the heart tissue for healthy cardiac functioning [44].

You may know that liver synthesises lipids [fats].

Daily consumption of Moringa can also regulate the lipid synthesis and reduce triglycerides levels and control overall cholesterol levels [45].

Therefore,

Adding Moringa in your daily diet is just a convenient method to help control some of dyslipidemia effects, without changing your diet habits much.

However,

Changing your dietary habits and using a customised nutrition diet plan will significantly help you!!

This clinical trial result also shows that 4.6 g-tablets of Moringa leaves, taken over a 50-day treatment period was effective to reduce:

  • total cholesterol,
  • triglycerides
  • low-density lipoprotein,
  • very-low-density lipoprotein cholesterol level
  • with the improvement of high-density lipoprotein, HDL  [40].

Heart attack

Cardio-tonic drugs are a standard treatment to improve cardiac functioning of heart attack patients [46].

Moringa acts as a cardiotonic [47] and may be helpful to improve heart functioning.

Stroke

Moringa containing bio-active phytochemicals like quercetin and alkaloids provides you with cardio-protective effects [39].

To some extent this benefit of Moringa might offer some protection from a stroke attack.

Moringa is also effective to control increased heart rate (tachycardia) and gives protection against stroke [48].

Blood pressure

Increased oxidative stress and resistance in the blood vessels leads to increased blood pressure.

Moringa leaves have the ability to modulate the vascular function and potent antioxidant properties.

Both of these therapeutic properties help Moringa to improve blood pressure in hypertensive subjects [49].

A recent human study reported consumption of 120 g of cooked Moringa leaves potentially lower both systolic and diastolic blood pressure [50].

How it helps bronchitis

If you or your close one gets affected by a seasonal bronchitis.

Moringa, the natural ingredient can help you to alleviate the condition.

The symptoms of bronchitis often make you worry, as chronic cough and breathlessness reduce the quality of life.

Bronchitis is an infectious condition associated with inflammation of airways.

Alkaloid Moringine derived from Moringa relaxes bronchioles.

In addition, the antipyretic, antispasmodic, anti-inflammatory effect of Moringa helps to provide some symptomatic relief.

If they don’t have any sensitivities or allergies you can give this herb to your children also.

Just make sure that no one including you has any particular food sensitivities or allergy to moringa.

This research shows that Moringa is a safe and effective alternative option for upper respiratory tract infections [51].

Moringa Combats Effectively Anemia

Iron deficiency anemia is more common in women.

Are you using an iron supplement?

I suggest why don’t you try Moringa leaf supplement?

In the earlier section in this article I have already show that Moringa contains 25% more iron content than spinach.

This will definitely help you to improve your hemoglobin level.

A human trial conducted on anemic women reported that a 200 mg Moringa tablet improves iron deficiency anemia in women [52].

In another human study, it has confirmed that Moringa significantly improves hemoglobin level and more effective in older patients than the younger aged group [53].

Eczema and skin disorders

Topical application of Moringa is effective to improve inflammatory skin disorders like atopic dermatitis or eczema [54].

But there is not much Moringa containing topical products that are formulated and marketed in the UK.

My research can ensure you that very soon Moringa containing products will spread in the UK market.

Moringa researchers have already found:

• 36 anti-inflammatory bio-active phytochemicals in Moringa leaves along with a rich source of multiple vitamins including

• Vit A, C, and D help to ameliorate eczema.

Here is a testimony of a user also explains moringa powder benefits on the skin against eczema:

“YES. I’ve had to deal with eczema for 35 years, daily applying cortisone to my face and all over the areas that may have gotten too much heat or sun. I’m on my 4th day of taking moringa and have no bumps or sign of eczema anywhere. And I spent 2 hours in the sun and 90-degree heat on the second day! It works. Not only for eczema – for everything!” [55]

You might already be aware that…

I am not selling moringa supplements.

This functional food could significantly support your weight loss, exercise recovery, mental performance and maximise your health.

Due to the fact that this plant is a very potent superfood I have decided to share with you at least some of the most important Moringa benefits.

 

  • If you would like to lose weight fast and safe, transform your body shape, fitness or health.

 

  • Or if you have any questions whatsoever regarding nutrition or supplementation please contact me now through this link  here, and I will get back to you in less than, 24 hours.

 

References: 

30. Kang Zi Khor, Vuanghao Lim, Emmanuel J. Moses, and Nozlena Abdul Samad, “The In Vitro and In VivoAnticancer Properties of Moringa oleifera,” Evidence-Based Complementary and Alternative Medicine, vol. 2018, Article ID 1071243, 14 pages, 2018. https://doi.org/10.1155/2018/1071243. Online available at https://www.hindawi.com/journals/ecam/2018/1071243/

31. Zayas-Viera, María Del Mar; Vivas-Mejia, Ph.D, Pablo; and Reyes, PhD, Jeyshka (2016) “Anticancer Effect of Moringa oleifera Leaf Extract in Human Cancer Cell Lines,” Journal of Health Disparities Research and Practice: Vol. 9 : Iss. 5 , Article 102.
Available at: https://digitalscholarship.unlv.edu/jhdrp/vol9/iss5/102. Online available athttps://digitalscholarship.unlv.edu/jhdrp/vol9/iss5/102/

32. Nurul Ashikin Abd Karim, Muhammad Din Ibrahim, SaieBrindhaKntayya, Yaya Rukayadi, Hazrulizawati Abd Hamid, Ahmad Faizal AbdullRazis. Moringa oleifera Lam: Targeting Chemoprevention. 10.14456/apjcp.2016.155/APJCP.2016.17.8.3675. Online available athttp://journal.waocp.org/article_33038_779fe5464be753c3717f3f80c0b6ebe0.pdf

33. V. Lobo, A. Patil, A. Phatak, N. Chandra. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Rev. 2010 Jul-Dec; 4(8): 118–126. doi: 10.4103/0973-7847.70902. Online available athttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249911/

34. Philip Hunter. The inflammation theory of disease: The growing realization that chronic inflammation is crucial in many diseases opens new avenues for treatment. EMBO Rep. 2012 Nov; 13(11): 968–970. Published online 2012 Oct 9. doi: 10.1038/embor.2012.142. Online available athttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492709/

35. Autoimmune Disease List. American Autoimmune Related Disease Association, Inc. Online available at https://www.aarda.org/diseaselist/

36. Gustavo Rodrigues Martins, Gabriela BottaroGelaleti, Marina GobbeMoschetta, Larissa BazelaMaschio-Signorini, and Debora Ap. Pires de Campos Zuccari, “Proinflammatory and Anti-Inflammatory Cytokines Mediated by NF-κB Factor as Prognostic Markers in Mammary Tumors,” Mediators of Inflammation, vol. 2016, Article ID 9512743, 10 pages, 2016. https://doi.org/10.1155/2016/9512743. Online available at https://www.hindawi.com/journals/mi/2016/9512743/

37. StanislavaVranková, Andrej Barta, Jana Klimentová, Ima Dovinová, Silvia Líšková, ZdenkaDobešová, OľgaPecháňová, Jaroslav Kuneš, Josef Zicha. The Regulatory Role of Nuclear Factor Kappa B in the Heart of Hereditary Hypertriglyceridemic Rat. Oxid Med Cell Longev. 2016; 2016: 9814038. Published online 2016 Apr 11. doi: 10.1155/2016/9814038. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842370/

38. Marcela Vergara-Jimenez, Manal Mused Almatrafi, Maria Luz Fernandez. Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease. Antioxidants (Basel) 2017 Dec; 6(4): 91. Published online 2017 Nov 16. doi: 10.3390/antiox6040091. Online available athttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745501/

39. The Structure, Function and Research Applications of the Hippocampus. Lonza. Online available at https://www.lonza.com/products-services/bioresearch/primary-cells/animal-cellsmedia/mouse-neural-cellsmedia/neural-knowledge-center/hippocampal-introduction

40. Raimunda Sâmia NogueiraBrilhante,Jamille AlencarSales,Vandbergue SantosPereira,Débora de Souza Collares MaiaCastelo-Branco,Rossana de AguiarCordeiro,Célia Mariade Souza Sampaio,Manoelde Araújo Neto Paiva,João Bosco Feitosa dosSantos,José Júlio CostaSidrim,Marcos Fábio GadelhaRocha.Research advances on the multiple uses of Moringa oleifera: A sustainable alternative for socially neglected population. Asian Pacific Journal of Tropical Medicine. Volume 10, Issue 7, July 2017, Pages 621-630. Online available athttps://www.sciencedirect.com/science/article/pii/S1995764516307143

41. ChatchadaSutalangka, JintanapornWattanathorn, SupapornMuchimapura, WipaweeThukham-mee. Moringa oleifera Mitigates Memory Impairment and Neurodegeneration in Animal Model of Age-Related Dementia. Oxid Med Cell Longev. 2013; 2013: 695936. Published online 2013 Dec. 23. doi: 10.1155/2013/695936. Online available athttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884855/

42. Michelle A. Harris, Trevor S. Ferguson, Michael S. Boyne, J. Peter Figueroa. High prevalence of dyslipidemia among primary care patients with hypertension and diabetes in Jamaica. Arch Med Sci Atheroscler Dis. 2017; 2: e61–e67. Published online 2017 Oct 5. doi: 10.5114/amsad.2017.70596. Online available athttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728072/

43. Gabriela Murillo, Manal Almatrafi, Marcela Vergara-Jimenez, and Maria Luz Fernandez. Moringa leaf powder modulate reverse cholesterol transport without changing plasma lipids in guinea. The FASEB Journal 2017 31:1_supplement, 647.2-647.2 Online available athttps://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.647.2

44. Leandro R. Marques, Tiego A. Diniz, Barbara M. Antunes, Fabrício E. Rossi, Erico C. Caperuto, Fábio S. Lira, Daniela C. Gonçalves. Reverse Cholesterol Transport: Molecular Mechanisms and the Non-medical Approach to Enhance HDL Cholesterol. Front Physiol. 2018; 9: 526. Published online 2018 May 15. doi: 10.3389/fphys.2018.00526. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962737/

45. Manal Mused Almatrafi, Marcela Vergara-Jimenez, Ana Gabriela Murillo, Gregory H. Norris, Christopher N. Blesso, Maria Luz Fernandez. Moringa Leaves Prevent Hepatic Lipid Accumulation and Inflammation in Guinea Pigs by Reducing the Expression of Genes Involved in Lipid Metabolism. Int J Mol Sci. 2017 Jul; 18(7): 1330. Published online 2017 Jun 22. doi: 10.3390/ijms18071330. Online available athttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535825/

46. Weber KT, Andrews V, Janicki JS. Cardiotonic agents in the management of chronic cardiac failure. Am Heart J. 1982 Apr;103(4 Pt 2):639-49. Online available at https://www.ncbi.nlm.nih.gov/pubmed/7064806

47. Jed W. Fahey. Moringa oleifera: A Review of the Medical Evidence for Its Nutritional, Therapeutic, and Prophylactic Properties. Part 1. Trees for Life Journal 2005, 1:5. Online available athttps://www.tfljournal.org/article.php/20051201124931586

48. DirekAekthammarat,PatchareewanPannangpetch,PanotTangsucharit. Moringa oleifera leaf extract lowers high blood pressure by alleviating vascular dysfunction and decreasing oxidative stress in L-NAME hypertensive rats. Phytomedicine. Volume 54, 15 February 2019, Pages 9-16. Online available athttps://www.sciencedirect.com/science/article/pii/S0944711318305440

49. Aekthammarat D, Pannangpetch P, Tangsucharit P. Moringa oleifera leaf extract lowers high blood pressure by alleviating vascular dysfunction and decreasing oxidative stress in L-NAME hypertensive rats. Phytomedicine. 2019 Feb 15;54:9-16. doi: 10.1016/j.phymed.2018.10.023. Epub 2018 Oct 19.Online available athttps://www.ncbi.nlm.nih.gov/pubmed/30668387

50. Chan Sun M, Ruhomally ZB, Boojhawon R, Neergheen-Bhujun VS. Consumption of Moringa oleifera Lam Leaves Lowers Postprandial Blood Pressure. J Am Coll Nutr. 2019 May 7:1-9. doi: 10.1080/07315724.2019.1608602. [Epub ahead of print]. Online available athttps://www.ncbi.nlm.nih.gov/pubmed/31063434

51. Babita Agrawal, Anita Mehta. Antiasthmatic activity of Moringa oleifera Lam: A clinical study. Indian J Pharmacol. 2008 Jan-Feb; 40(1): 28–31. doi: 10.4103/0253-7613.40486. Online available athttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023118/

52. Dona Suzana, Franciscus D. Suyatna, Azizahwati, RetnosariAndrajati, Santi Purna Sari, Abdul Mun’im. Effect of Moringa oleifera Leaves Extract Against Hematology and Blood Biochemical Value of Patients with Iron Deficiency Anemia. Journal of Young Pharmacists, 2017; 9(1s):S79-S84. doi:10.5530/jyp.2017.1s.20. Online available athttp://www.jyoungpharm.org/article/970

53. Madeeha Munir. Impact of Dried Moringa Oleifera Leaves in Enhancing Hemoglobin Status. ClinicalTrial.gov. U.S. National Library of Medicine. Online available athttps://clinicaltrials.gov/ct2/show/NCT03514472

54. Eun-JuChoi,TrishnaDebnath,YujiaoTang,Young-BaeRyu,Sang-HoMoon,Eun-KyungKim. Topical application of Moringa oleifera leaf extract ameliorates experimentally induced atopic dermatitis by the regulation of Th1/Th2/Th17 balance. Biomedicine & Pharmacotherapy. Volume 84, December 2016, Pages 870-877. Online available at
https://www.sciencedirect.com/science/article/abs/pii/S0753332216310435

55. Moringa and Eczema. Moringa Harvest. Online available at https://www.moringaharvest.co.uk/pages/eczema

Write a comment

Scroll To Top